There currently are a variety of options to travel by night bus or night train from Frankfurt am Main (Germany) to Prague (Czech Republic), taking between approximately 6 and 10 hours: Namely the BUS Amsterdam - Praha and the EN 40459. These lines are operated by Regiojet and ÖBB.

Next offers

Regiojet

Regiojet operates both night trains and night buses across Europe, providing various travel options.

What do Regiojet night trains offer?

Regiojet night trains offer a range of cabin options, from standard reclining seats in open compartments to private couchette cabins designed for one to four travelers, complete with bedding and duvets for a restful journey. Wifi is available and breakfast and coffee are served for free.

What are the night buses like?

Regiojet night buses feature ergonomic seating that can recline for comfort, with generous legroom and amenities such as USB charging ports, free WiFi, personal entertainment screens, and complimentary refreshments available during the journey. There is also a toilet on the bus.

ÖBB

The Austrian Federal Railways (ÖBB) operate the Nightjet and Euronight trains (the latter together with other national railway agencies).

What types of carriages are available on ÖBB trains?

The ÖBB usually offer three types of carriages in their night trains: seats, couchettes, and sleepers.

What's the difference between seats, couchettes, and sleeper cars?

Seats are for the bravest, while couchettes and sleepers provide a more comfortable journey. In the couchettes, you can find simple and rather narrow berths, while the sleepers are equipped with proper beds and sometimes even a private bathroom. Couchettes accommodate up to six people, while sleepers are private compartments for one to three people.

What amenities do sleeper cars offer?

They sometimes include a private bathroom or even a shower, sometimes only a sink.

For the next 7 dates with connections, the cheapest offer starts at 26 EUR. Check our connection pages below for all availabilities!

Offers on the date of your choice

Next available offers

Sat, 13.09.2025

from 41 EUR

Sun, 14.09.2025

from 41 EUR

Mon, 15.09.2025

from 26 EUR

Tue, 16.09.2025

from 26 EUR

Wed, 17.09.2025

from 26 EUR

Thu, 18.09.2025

from 26 EUR

Fri, 19.09.2025

from 26 EUR